In this off-the-wall road comedy, John (Ethan Suplee) and Sam (Kevin Connolly) are a pair of close friends who are in need of a vacation, so they hit the road from their hometown of Washington, D.C., to New Orleans, hoping to check out the action at Mardi Gras. Along the way, however, they manage to run over someone with their car; their victim, Tyrone (Coolio), is an escaped convict who dies shor